Oncology Central

Fibrosis, cancer and the premetastatic niche

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The onset and development of breast cancer is known to be a complex process involving reciprocal interactions between multiple cell types within the body. Epithelial, endothelial, mesenchymal and hematopoietic cells act together to alter and shape the microenvironment of the tumor to modulate the initiation, progression and dissemination of cancer.

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