Original Publication Date: 1 September, 2014
Publication / Source: Breast Cancer Management
Authors: Wenfeng Xia, Wiendelt Steenbergen, Srirang Manohar
Breast cancer is the most frequently occurring malignancy in women, and the leading cause of cancer death, with up to 0.5 million mortalities in 2008 . The strategy to reduce breast cancer deaths is by early detection, reliable diagnosis and effective treatments. The standard imaging modality for breast cancer detection by screening asymptomatic women is x-ray imaging. Diagnosis is performed after the triple assessment of x-ray mammography, ultrasonography and biopsy. MRI is used in specific problem-solving situations, such as when contradictory results are obtained from x-ray and ultrasound images. x-ray mammography is capable of producing 2D projection images with a high spatial resolution. However, x-ray mammography, besides possessing ionizing hazards and requiring painful breast compression, is less sensitive in dense breasts .