Oncology Central

Clinical value of isoform-specific detection and targeting of AKT1, AKT2 and AKT3 in breast cancer

0

Overactivation of the PI3K/AKT signaling pathway is frequently reported in breast cancer, consequently inhibitors targeting this pathway are clinically useful. AKT constitutes a hub in the regulation of several cancer hallmarks, such as proliferation, survival and migration. Three AKT isoforms, named AKT1, AKT2 and AKT3, are identified in humans.

To view restricted content, please:
Share:

Leave A Comment