Original Publication Date: 1 October, 2014
Publication / Source: Future Oncology
Authors: Marcello Maugeri-Saccà, Patrizia Vici, Luigi Di Lauro et al
Overcoming resistance to standard anticancer treatments represents a significant challenge. The interest regarding cancer stem cells, a cellular population that has the ability to self-renew and to propagate the tumor, was prompted by experimental evidence delineating the molecular mechanisms that are selectively activated in this cellular subset in order to survive chemotherapy.