Original Publication Date: 1 September, 2014
Publication / Source: Immunotherapy
Authors: Thiranut Ramutton, Simona Buccheri, Francesco Dieli et al
γδ T cells are capable of recognizing tumor cells and exert potent cellular cytotoxicity against a large range of tumors, including colon cancer. However, tumors utilize numerous strategies to escape recognition or killing by patrolling γδ T cells, such as downregulation of NKG2D ligands, MICA/B and ULBPs.