Oncology Central

γδ T cells as a potential tool in colon cancer immunotherapy

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γδ T cells are capable of recognizing tumor cells and exert potent cellular cytotoxicity against a large range of tumors, including colon cancer. However, tumors utilize numerous strategies to escape recognition or killing by patrolling γδ T cells, such as downregulation of NKG2D ligands, MICA/B and ULBPs.

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