Original Publication Date: 1 July, 2014
Publication / Source: Clinical Investigation
Authors: Ozkan Kanat, Bert H O’Neil
Cachexia is one of the most distressing and devastating experiences for cancer patients. It is now considered a complex, multifactorial metabolic syndrome characterized by anorexia, progressive and uncontrollable weight loss, fatigue, progressive depletion of adipose tissue and skeletal muscle, systemic inflammation, insulin resistance, abnormalities in the metabolism of carbohydrate, protein and lipid, as well as impaired immune function [1–3].