Original Publication Date: 1 September, 2014
Publication / Source: International Journal of Endocrine Oncology
Authors: Guido Rindi, Frediano Inzani
Grading neoplasms is meant to associate morphology to increased death risk. This is the core of histopathology work and demands well-defined and reproducible histopathological criteria, together with stringent clinical observation. The rule says the higher the grade the worse the prognosis. This is likely the simplest method to associate tumor biology as depicted by morphology – the face of cancer – to clinical behavior.