Original Publication Date: 1 June, 2014
Publication / Source: Biomarkers in Medicine
Authors: Dimitra K Alexopoulou, Christos K Kontos, Spyridon Christodoulou, Iordanis N Papadopoulos, Andreas Scorilas
Background: Dysregulated expression of several KLK family members has been observed in colorectal adenocarcinoma. In the present study, the prognostic value of KLK11 mRNA expression as a molecular tissue biomarker in colorectal adenocarcinoma was examined. Materials & methods: Using quantitative real-time PCR, KLK11 mRNA expression was studied in 120 cancerous and 41 paired noncancerous colorectal specimens obtained from 120 patients with primary colorectal adenocarcinoma.