Original Publication Date: 3 June, 2014
Publication / Source: Biomarkers in Medicine
Authors: Dong-Joo Cheon & Sandra Orsulic
Survival rates for advanced stage ovarian cancer have not changed significantly over the past 40 years and ovarian cancer remains the most lethal gynecologic cancer in women. The most common type of ovarian cancer, and the one that accounts for the majority of deaths from ovarian cancer, is serous papillary carcinoma. Approximately 20% of patients with this ovarian cancer subtype are intrinsically resistant to chemotherapy or develop chemoresistant disease within 1 year from initial treatment.