Original Publication Date: 4 April, 2014
Publication / Source: Future Oncology
Authors: Pol Specenier
Induction chemotherapy is not to be considered standard of care in locally advanced (LA) squamous cell carcinoma of the head and neck (SCCHN) . The coffin of induction chemotherapy is even about to be nailed . The causes of the apparently imminent demise are diverse. SCCHN is a heterogeneous disease with prognosis depending on tumor site, T and N stage, etiology of the disease (human papilloma virus, smoking or drinking). Consequently, in order to include sufficient patients, most induction chemotherapy trials enrolled patients with a wide variation in risk of local and/or distant relapse.