Original Publication Date: 1 April, 2014
Publication / Source: Future Oncology
Authors: Mazen Mislmani, Heidi Frasure, Somu Suppiah, Jeffrey Fabien, Simon S Lo, Robert Debernardo & Charles A Kunos
Aims: The aim of this study was to assess acute and subacacute gastrointestinal toxicity after fractionated stereotactic ablative radiotherapy (SABR) in women having recurrent gynecological cancers in the upper abdomen. Materials & methods: In total, 34 women underwent upper abdominal SABR (24 Gy/three divided 8 Gy consecutive daily doses) using a robotic Cyberknife® (Accuray, CA, USA) platform. Volumes of the duodenum receiving 10% increments of the prescription dose were associated to post-therapy gastrointestinal toxicities using binary logistic regression analyses.