Oncology Central

Serrated polyps and colorectal cancer risk


Colorectal cancer is among the three most common cancers in the World with a global incidence exceeding 1.2 million new cases and 600,000 deaths per year; yet most cases could be prevented by endoscopic removal of precursor lesions. Efficient screening and follow-up are the best options to reduce the cancer burden caused by colorectal cancer (CRC). Therefore, it is essential to know which colorectal polyps have the potential to progress into cancer. During the last decade, serrated polyps have emerged as the second most important group of CRC precursor lesions, in addition to conventional adenomatous polyps. It has been estimated that up to 30–35% of CRCs have their origin in serrated polyps.

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