Original Publication Date: 28 January, 2014
Publication / Source: Nanomedicine
Authors: Guangjun Nie & Yuliang Zhao
High sensitivity and specificity imaging of tumors is critical for early tumor detection, effective treatment and prognosis. However, this is challenging owing to the nature of tumors emerging from normal tissues, along with aging and their high degree of complexity. Recent rapid development of functional nanomaterials offers new opportunities for tumor imaging with enhanced capacities for tumor targeting and high sensitivity . In addition to the beneficial properties for tumor imaging, these chemically engineered nanomaterials usually introduced new concerns, such as potential nanotoxicity, lack of biocompatibility and difficulty for integrated functionality [2,3].