Original Publication Date: 27 November, 2013
Publication / Source: International Journal of Hematologic Oncology
Authors: Elizabeth L Alexander, Michael J Satlin, Maria N Gamaletsou, Nikolaos V Sipsas & Thomas J Walsh
The emergence of infections due to multidrug-resistant (MDR) bacteria poses a major public health threat to all patients, but patients with hematologic malignancies are especially at risk. A common thread across all classes of bacteria is that increased reliance on and usage of broad-spectrum antibacterial agents, combined with the intrinsic ability of bacteria to develop and transmit resistance-conferring mutations, has led to the widespread dissemination of MDR organisms.