Oncology Central

Particle therapy: a suitable alternative to stereotactic body radiotherapy for stage I non-small-cell lung cancer?


Many new particle therapy centers are now under construction all over the world. In Japan, ten centers (one center with a proton and carbon accelerator, two centers with a carbon accelerator and seven centers with a proton accelerator) are now in service, and four are now preparing for the start of clinical service or under construction as of July 2013. Nearly 20 years have passed since the National Institute for Radiological Sciences (NIRS) in Chiba (Japan), started carbon-ion therapy in 1994. Long-term results of particle therapy, including those on stage I non-small-cell lung cancer (NSCLC), are gradually accumulating. Recently, clinical results of particle therapy with a median follow-up of 51 months for patients with T2a/bN0M0 NSCLC have been published from the Hyogo Ion Beam Medical Center (HIBMC) in Japan; of the 70 patients reported, 43 were treated with proton beams and 27 received carbon-ion therapy [1].

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