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0ASTRO16 news round-up

Read our summaries of some of the key data presented this week at the 58th Annual Meeting of the American Society for Radiation Oncology (ASTRO16).

Journal Articles

Brain and neurologic

ASTRO16 news round-up

Whole brain radiotherapy for lung cancer brain metastases: little clinical benefit demonstrated

Exploiting molecular biology for diagnosis and targeted management of pediatric low-grade gliomas

Breast

Implantable device may help limit metastatic spread of breast cancer

A meta-analysis of biomarkers for the prognosis of triple-negative breast cancer patients

GE Healthcare: Innovation to improve breast cancer diagnostics

Colorectal

Checkpoint inhibition for colorectal cancer: progress and possibilities

Colorectal cancer stem cells could be targeted with novel Wnt inhibitor

DNA methylation patterns as noninvasive biomarkers and targets of epigenetic therapies in colorectal cancer

Endocrine

The role of epigenetics and long noncoding RNA MIAT in neuroendocrine prostate cancer

Targeting PI3K isoform shows therapeutic promise in pancreatic neuroendocrine tumors

New treatment hopes for patients with inoperable neuroendocrine cancers?

Gastrointestinal

Selective internal radiation therapy in treatment of hepatocellular carcinoma: new concepts of personalization

Conformal radiotherapy as a bridge to liver transplantation for hepatocellular carcinoma: is it safe?

RSP6KB1–VMP1 fused gene offers new disease insight in esophageal cancer

Genitourinary

Metabolism genes may embody marker of response to nivolumab in renal cell carcinoma

Systemic therapy for metastatic bladder cancer in 2016 and beyond

New research could help personalize treatment in early bladder cancer

Gynecologic

Sticky nanoparticles for a tricky issue: improving drug delivery for gynecological cancer

Study demonstrates the importance of regular cervical cancer screening

Ovarian cancer: SOX2 & SIK2 may represent novel diagnostic marker/therapeutic target

Head and neck

Most detailed image of head and neck cancer stem cells to date revealed

Induction chemotherapy for head and neck cancer: is there still a role?

US FDA grant approval of pembrolizumab for advanced head & neck cancer

Hematologic

3D tissue-engineered bone marrow: what does this mean for the treatment of multiple myeloma?

Promising results demonstrated for CAR-T therapy in advanced non-Hodgkin lymphoma patients

Key signaling pathway for leukemia cells identified

Lung

ASTRO16 news round-up

Effectiveness of four PD-L1 tests compared

Nanoparticles developed to distinguish between cancerous and healthy lung cells

Pancreatic

Prolonging the survival of advanced pancreatic cancer patients with a novel immunotherapy drug

Pancreatic cancer screening using a multiplatform human serum metabolomics system

Unique pancreatic cancer cell survival mechanism uncovered

Prostate

ASTRO16 news round-up

First results from ProtecT trial in prostate cancer published

Study suggests method to individualize treatment in metastatic prostate cancer

Rare tumors

Low-dose brachytherapy strategies to treat uveal melanoma: is less more?

Should clinical trials be approached differently for rare cancers?

Novel targets for natural killer/T-cell lymphoma immunotherapy

Skin

Melanoma brain metastases: promising results for immune and targeted therapies combined with radiosurgery

Role of rare germline copy number variation in melanoma-prone patients

Research suggests experimental drug could stop melanoma and other cancers