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Journal Articles

LungDNA biomarker
0EGFR mutations in lung cancer: from tissue testing to liquid biopsy

In order to assess the sensitivity of NSCLCs to EGFR tyrosine kinase inhibitors, tumor DNA has to be tested for EGFR mutations. With the limitations of current DNA sources in the disease, this article discusses use of circulating free tumor DNA or circulating tumor cells as a new strategy for tumor genotyping.

Brain and neurologic

Gene signature indicative of survival identified in glioblastoma

Neuropathic cancer pain eliminated with gene therapy

Personalized medicine in neuro-oncology

Breast

One dose, one treatment, one day - interview with Richard Simcock

Chemotherapy duo powerful against breast cancer stem cells in preclinical study

What if you had a new exam that could help you give your patients a quick and confident diagnosis in breast cancer care?

Colorectal

Metformin use may lower risk of cancer among postmenopausal women with diabetes

Colorectal cancer – coffee consumption associated with reduced risk?

Different modalities for colorectal cancer screening: experiences in The Netherlands so far

Endocrine

New treatment hopes for patients with inoperable neuroendocrine cancers?

Risk-stratified follow-up of patients with medullary thyroid carcinoma

The challenge of managing adrenocortical carcinoma: two case studies

Gastrointestinal

Current advances in targeted therapies for metastatic gastric cancer: improving patient care

Tumors may resist treatment by ‘stealing’ blood vessels

The clinical role of ‘liquid biopsy’ in hepatocellular carcinoma

Genitourinary

Kidney cancer therapy could be boosted by common supplement

Clinical management of metastatic kidney cancer: the role of new molecular drugs

Checkpoint inhibitors in bladder and renal cancers: results and perspectives

Gynecologic

AACR16: Genomic profiling could advance research for poorly responsive gynecologic cancers

Metformin use may lower risk of cancer among postmenopausal women with diabetes

Potential therapy target identified in ovarian serous cancer

Head and neck

Dr Lisa Licitra discusses the current and future treatment landscape in recurrent/metastatic head and neck cancer

Possible new target for oral cancer therapy uncovered

Panel discussion with leading medical oncologists on the continuum of care in recurrent/metastatic head and neck cancer

Hematologic

Infographic: Pixantrone–rituximab versus gemcitabine–rituximab in relapsed/refractory aggressive non-Hodgkin lymphoma

BET inhibitors reduce tumor growth via apoptosis

Pixantrone–rituximab versus gemcitabine–rituximab in relapsed/refractory aggressive non-Hodgkin lymphoma

Lung

EGFR mutations in lung cancer: from tissue testing to liquid biopsy

SBRT may increase the risk of noncancer deaths in lung cancer patients

The challenge of small lung nodules identified in CT screening: can biomarkers assist diagnosis?

Pancreatic

Specific mouth bacteria linked to increased pancreatic cancer risk

AACR16: Could pancreatic cancer be treated with engineered T cells?

Immune-stimulating combination promotes response in locally advanced pancreatic cancer

Prostate

New light shed on initiation of metastasis in prostate cancer

Immunosuppressive prostate cancer therapies may promote relapse

Germline genetic profiling in prostate cancer: latest developments and potential clinical applications

Rare tumors

Personalized cancer therapy for soft tissue sarcomas: progress and pitfalls

The Rare Tumor Initiative in the National Cancer Institute: Harnessing expertise and existing resources to better develop therapies for rare tumors

Rare tumors: an eye on the future

Skin

Advanced melanoma patient in remission 5 years after combination immunotherapies

The role of radiation therapy in the management of cutaneous melanoma

Combination radiotherapy and immunotherapy continues to show promise in melanoma